The needle cap is not made with natural rubber latex. DUPIXENT is provided as a single-dose pre-filled syringe with needle shield in a 2.25 mL siliconized Type-1 clear glass syringe. Dupilumab has an approximate molecular weight of 147 kDa.ĭupilumab is produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture.ĭUPIXENT (dupilumab) Injection is supplied as a sterile, preservative-free, clear to slightly opalescent, colorless to pale yellow solution for subcutaneous injection.
DESCRIPTIONĭupilumab, an interleukin-4 receptor alpha antagonist, is a human monoclonal antibody of the IgG4 subclass that binds to the IL-4Rα subunit and inhibits IL-4 and IL-13 signaling. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. These are not all the possible side effects of Dupixent. Tell the doctor if you have any side effect that bothers you or that does not go away.
It is not known if Dupixent is safe and effective in children younger than 6 years of age. Find Lowest Prices on What is Dupixent and how is it used?ĭupixent (dupilumab) injection is aninterleukin-4 receptor alpha- antagonist indicated for the treatment of patients with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable as an add-on maintenance treatment of adult and pediatric patients aged 6 years and older with moderate-to-severe asthma characterized by an eosinophilic phenotype or with oral corticosteroid dependent asthma as an add-on maintenance treatment in adult patients with inadequately controlled chronic rhinosinusitis with nasal polyposis (CRSwNP), and for the treatment of adult and pediatric patients aged 12 years and older, weighing at least 40 kg, with eosinophilic esophagitis (EoE).ĭupixent belongs to a class of drugs called Interleukin Inhibitors.
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